{
  "_id": "6acdf046a14063b82c3ad45b",
  "Type": "Package",
  "Package": "messi",
  "Title": "Mediation with External Summary Statistic Information",
  "Version": "0.1.2",
  "Description": "Fits the MESSI, hard constraint, and unconstrained models\nin Boss et al. (2023) <doi:10.48550/arXiv.2306.17347> for\nmediation analyses with external summary-level information on\nthe total effect.",
  "Authors@R": "c(\nperson(given = \"Jonathan\", family = \"Boss\", role = c(\"aut\"), email = \"bossjona@umich.edu\"),\nperson(given = \"Bhramar\", family = \"Mukherjee\", role = c(\"aut\"), email = \"bhramar@umich.edu\"),\nperson(given = \"Michael\", family = \"Kleinsasser\", role = c(\"cre\"), email = \"mkleinsa@umich.edu\")\n)",
  "Maintainer": "Michael Kleinsasser <mkleinsa@umich.edu>",
  "License": "GPL-2",
  "Encoding": "UTF-8",
  "LazyData": "true",
  "Biarch": "true",
  "URL": "https://github.com/umich-cphds/messi",
  "BugReports": "https://github.com/umich-cphds/messi/issues",
  "Roxygen": "list(markdown = TRUE)",
  "RoxygenNote": "7.3.2",
  "Repository": "https://umich-cphds.r-universe.dev",
  "Date/Publication": "2025-01-06 15:04:55 UTC",
  "RemoteUrl": "https://github.com/umich-cphds/messi",
  "RemoteRef": "HEAD",
  "RemoteSha": "ead6a4f13f9bc69158981f7c0ad082baa843b6b3",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-10-13 08:38:06 UTC",
    "User": "root"
  },
  "Author": "Jonathan Boss [aut],\nBhramar Mukherjee [aut],\nMichael Kleinsasser [cre]",
  "_user": "umich-cphds",
  "_type": "src",
  "_file": "messi_0.1.2.tar.gz",
  "_fileid": "https://r2.ropensci.org/ffeafa548df27d53468b5dc6ca73f8ba3078e4b8dac8cf550136790ca8d4c458",
  "_filesize": 289497,
  "_sha256": "ffeafa548df27d53468b5dc6ca73f8ba3078e4b8dac8cf550136790ca8d4c458",
  "_expires": "2027-01-21T08:48:04.000Z",
  "_created": "2026-10-13T08:38:06.000Z",
  "_published": "2026-10-13T08:48:06.259Z",
  "_buildurl": "https://github.com/r-universe/umich-cphds/actions/runs/38370253200",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_jobs": [
    {
      "job": 115206440013,
      "time": 141,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11798689233"
    },
    {
      "job": 115206440028,
      "time": 106,
      "config": "linux-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11798154163"
    },
    {
      "job": 115206440328,
      "time": 94,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "11799991225"
    },
    {
      "job": 115206440148,
      "time": 108,
      "config": "macos-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11798474953"
    },
    {
      "job": 115205303720,
      "time": 174,
      "config": "source",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11798039998"
    },
    {
      "job": 115206440046,
      "time": 88,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "11798609260"
    },
    {
      "job": 115206440221,
      "time": 82,
      "config": "windows-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11798543409"
    },
    {
      "job": 115206440063,
      "time": 86,
      "config": "windows-oldrel-x86_64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "11798323895"
    },
    {
      "job": 115206440034,
      "time": 93,
      "config": "windows-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11798184035"
    }
  ],
  "_upstream": "https://github.com/umich-cphds/messi",
  "_commit": {
    "id": "ead6a4f13f9bc69158981f7c0ad082baa843b6b3",
    "author": "Michael Kleinsasser <mkleinsa@umich.edu>",
    "committer": "Michael Kleinsasser <mkleinsa@umich.edu>",
    "message": "cran requests arXiv doi in different format\n",
    "time": 1736175895
  },
  "_maintainer": {
    "name": "Michael Kleinsasser",
    "email": "mkleinsa@umich.edu",
    "login": "mkleinsa",
    "description": "R programmer for the Department of Biostatistics at the University of Michigan, Ann Arbor. M.S. Statistics. ",
    "uuid": 39565600
  },
  "_distro": "resolute",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 3.6.2",
      "role": "Depends"
    },
    {
      "package": "MASS",
      "role": "Imports"
    },
    {
      "package": "ggplot2",
      "role": "Imports"
    },
    {
      "package": "patchwork",
      "role": "Imports"
    },
    {
      "package": "progress",
      "role": "Imports"
    }
  ],
  "_owner": "umich-cphds",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [],
  "_tags": [],
  "_stars": 0,
  "_contributors": [
    {
      "user": "mkleinsa",
      "count": 16,
      "uuid": 39565600
    },
    {
      "user": "bossjona",
      "count": 3,
      "uuid": 23487687
    }
  ],
  "_userbio": {
    "uuid": 38891577,
    "type": "organization",
    "name": " Center for Precision Health Data Science",
    "followers": 11,
    "description": "University of Michigan  Center for Precision Health Data Science"
  },
  "_downloads": {
    "count": 232,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/messi"
  },
  "_devurl": "https://github.com/umich-cphds/messi",
  "_searchresults": 2,
  "_rbuild": "4.6.1",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/manual.pdf",
    "extra/messi.html",
    "extra/readme.html",
    "extra/readme.md"
  ],
  "_homeurl": "https://github.com/umich-cphds/messi",
  "_realowner": "umich-cphds",
  "_cranurl": true,
  "_releases": [
    {
      "version": "0.1.1",
      "date": "2023-07-13"
    },
    {
      "version": "0.1.2",
      "date": "2025-01-09"
    }
  ],
  "_exports": [
    "messi",
    "plot_messi"
  ],
  "_datasets": [
    {
      "name": "Med",
      "title": "Simulated data with real mediation effect",
      "object": "Med",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "nullMed",
      "title": "Simulated data with null mediation effect",
      "object": "nullMed",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "constrained.unpenalized",
      "title": "Estimate hard constraint model parameters using cyclical coordinate descent.",
      "topics": [
        "constrained.unpenalized"
      ]
    },
    {
      "page": "Med",
      "title": "Simulated data with real mediation effect",
      "topics": [
        "Med"
      ]
    },
    {
      "page": "messi",
      "title": "Implementation of Mediation with External Summary Statistic Information (MESSI) from Boss et al. (2024).",
      "topics": [
        "messi"
      ]
    },
    {
      "page": "nullMed",
      "title": "Simulated data with null mediation effect",
      "topics": [
        "nullMed"
      ]
    },
    {
      "page": "plot_messi",
      "title": "Forestplot to Summarize Estimation and Inference on alpha_a and beta_m.",
      "topics": [
        "plot_messi"
      ]
    },
    {
      "page": "rand.eff.coord.desc.unpenalized",
      "title": "Cyclical coordinate descent algorithm for the M-step in the EM Algorithm for the maximizing the soft constraint model likelihood.",
      "topics": [
        "rand.eff.coord.desc.unpenalized"
      ]
    },
    {
      "page": "rand.eff.unpenalized",
      "title": "Estimate soft constraint model parameters using the EM algorithm.",
      "topics": [
        "rand.eff.unpenalized"
      ]
    },
    {
      "page": "unconstrained.unpenalized",
      "title": "Estimate unconstrained model parameters.",
      "topics": [
        "unconstrained.unpenalized"
      ]
    }
  ],
  "_readme": "https://github.com/umich-cphds/messi/raw/HEAD/README.md",
  "_rundeps": [
    "cli",
    "cpp11",
    "crayon",
    "farver",
    "ggplot2",
    "glue",
    "gtable",
    "hms",
    "isoband",
    "labeling",
    "lifecycle",
    "MASS",
    "patchwork",
    "pkgconfig",
    "prettyunits",
    "progress",
    "R6",
    "RColorBrewer",
    "rlang",
    "S7",
    "scales",
    "vctrs",
    "viridisLite",
    "withr"
  ],
  "_score": 2.6989700043360187,
  "_indexed": true,
  "_nocasepkg": "messi",
  "_universes": [
    "umich-cphds",
    "mkleinsa"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "0.1.2",
      "date": "2026-10-13T08:40:22.000Z",
      "distro": "resolute",
      "commit": "ead6a4f13f9bc69158981f7c0ad082baa843b6b3",
      "fileid": "https://r2.ropensci.org/f5531645294f5f80ba96ac778f99ddaf8fdeb19da778fb2081685b9569e50ce5",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/umich-cphds/actions/runs/38370253200"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "0.1.2",
      "date": "2026-10-13T08:39:44.000Z",
      "distro": "resolute",
      "commit": "ead6a4f13f9bc69158981f7c0ad082baa843b6b3",
      "fileid": "https://r2.ropensci.org/0b101c1a3ca132cb5340990eb4f5bfbde8477b8f511942839190cf144a1f3431",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/umich-cphds/actions/runs/38370253200"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "0.1.2",
      "date": "2026-10-13T08:47:16.000Z",
      "commit": "ead6a4f13f9bc69158981f7c0ad082baa843b6b3",
      "fileid": "https://r2.ropensci.org/f00abf366ecaf3e293a05f28198ce9f36c56e2e235999b40158e84fabd6a0b1e",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/umich-cphds/actions/runs/38370253200"
    },
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "0.1.2",
      "date": "2026-10-13T08:47:29.000Z",
      "commit": "ead6a4f13f9bc69158981f7c0ad082baa843b6b3",
      "fileid": "https://r2.ropensci.org/c778aae88df72a0c9c932df7dc36fc1e686db745d68ebe1b7dee1fbffe63a60b",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/umich-cphds/actions/runs/38370253200"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "0.1.2",
      "date": "2026-10-13T08:39:51.000Z",
      "commit": "ead6a4f13f9bc69158981f7c0ad082baa843b6b3",
      "fileid": "https://r2.ropensci.org/6482eaf5b58adf89587d7f9bc106f8ea2f78bc1b32e75ee621efbfec9dc26c75",
      "status": "success",
      "buildurl": "https://github.com/r-universe/umich-cphds/actions/runs/38370253200"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "0.1.2",
      "date": "2026-10-13T08:39:11.000Z",
      "commit": "ead6a4f13f9bc69158981f7c0ad082baa843b6b3",
      "fileid": "https://r2.ropensci.org/b3594c42c9f725f42a94212b4488a2979d15dad08e59b4471cee9376d2098a9d",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/umich-cphds/actions/runs/38370253200"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "0.1.2",
      "date": "2026-10-13T08:39:16.000Z",
      "commit": "ead6a4f13f9bc69158981f7c0ad082baa843b6b3",
      "fileid": "https://r2.ropensci.org/7ae980c4a5dd28a41849a74f759cb8ebe7c4a313fd84188206f777571ff7c088",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/umich-cphds/actions/runs/38370253200"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "0.1.2",
      "date": "2026-10-13T08:39:24.000Z",
      "commit": "ead6a4f13f9bc69158981f7c0ad082baa843b6b3",
      "fileid": "https://r2.ropensci.org/484b75e0135ee7de9d4b8d828ecacb42e08f9cd095fecae819714bbe56c1a5df",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/umich-cphds/actions/runs/38370253200"
    }
  ]
}